Antidiuretic hormone (also known as vasopressin) is synthesized in the hypothalamus and stored in the posterior pituitary gland. Upon release, it enters the circulatory system and is transported throughout the body. This hormone’s mechanism of action relies on its ability to reach specific receptor sites located on cells within the kidneys. These target cells play a crucial role in regulating water reabsorption.
This targeted delivery system is essential for maintaining fluid balance, blood pressure regulation, and overall physiological homeostasis. Dysregulation of this hormones transport or its interaction with target cells can lead to conditions such as diabetes insipidus, characterized by excessive thirst and urination. Understanding the transport mechanisms of this hormone has been instrumental in developing treatments for such disorders.
